Montemac-FX (Macleods Pharmaceuticals) is a prescription tablet that combines montelukast 10 mg and fexofenadine 120 mg. It is used to relieve allergy symptoms such as sneezing, runny nose and watery eyes.
Last reviewed: November 2026. General information only, not medical advice. Contents and strengths can differ by manufacturer and batch, so always check your pack and follow your doctor.
Quick Facts
| Brand | Montemac-FX (Macleods Pharmaceuticals) |
| Form | Tablet, strip of 10 |
| Per tablet | Montelukast 10 mg and fexofenadine 120 mg |
| Used for | Allergic rhinitis and allergy symptoms |
| Prescription | Required. Not habit forming |
| Storage | Below 25 degrees Celsius |
Montemac FX Composition
- Montelukast (10 mg): a leukotriene blocker that reduces inflammation in the nose and airways.
- Fexofenadine (120 mg): a non-drowsy-type antihistamine that blocks histamine.
What Is Montemac FX Used For?
- Sneezing and runny nose
- Stuffy or blocked nose
- Watery, itchy eyes and congestion from allergies
How It Works
Fexofenadine blocks histamine, which causes sneezing and itching. Montelukast reduces swelling and inflammation of the nose and airways. Together they cover two parts of an allergic reaction.
How to Take It
Take it as advised by your doctor, with or without food. Swallow it whole and do not chew, crush or break it. Taking more does not work better and may add side effects.
Possible Side Effects
Possible side effects include:
- Upper respiratory tract infection symptoms
- Headache, dizziness or sleepiness
- Nausea, vomiting or diarrhoea
- Skin rash or flu-like symptoms
Seek medical help for mood or behaviour changes, nightmares, thoughts of self-harm, swelling of the face, or breathing trouble.
Precautions and Who Should Be Careful
- Avoid alcohol, which can increase sleepiness.
- Avoid driving until you know how it affects you.
- Avoid apple, orange and grapefruit juice around the time of the dose, as they may reduce how well fexofenadine works.
- Use caution in kidney disease, as the dose may need adjusting.
- Ask your doctor in pregnancy or breastfeeding.
- Stop it at least 3 days before an allergy skin test, because it can affect the result.
Key Points to Remember
- It treats allergy symptoms. It is not for an asthma attack that is already happening.
- Avoid fruit juices near the dose.
- Report any mood or sleep changes, especially in children.
When to Contact a Doctor
- Mood changes, agitation, nightmares or thoughts of self-harm
- Wheezing or breathing trouble
- Rash or swelling of the face or lips
- Allergy symptoms not improving after a couple of weeks
Practical Tips
- Identify and avoid your triggers such as dust, pollen or pets.
- Wash bedding in hot water and keep windows shut on high-pollen days.
- Take it at the same time each day.
- Rinse your nose with saline water to ease congestion.
Questions to Ask Your Doctor or Pharmacist
- What am I allergic to and should I be tested?
- How long should I take this?
- Is it safe for my child or for me with my other conditions?
- Do I need to stop it before an allergy test?
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Helpful Video
Frequently Asked Questions
Is Montemac FX a steroid?
No. It contains an antihistamine and a leukotriene blocker, not a steroid.
Can I take Montemac FX with fruit juice?
It is best to avoid apple, orange and grapefruit juice around the dose, as they can reduce absorption of fexofenadine.
Does Montemac FX make you sleepy?
It can cause sleepiness or dizziness in some people, so be careful when driving.
Is Montemac FX habit forming?
No, it is listed as not habit forming.
Further reading: MedlinePlus (NIH): Montelukast
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