Methoben (Cardeon Formulations) is a tablet that combines alpha lipoic acid, methylcobalamin (B12), benfotiamine, folic acid, pyridoxine (B6) and chromium picolinate. It is used for nutritional support and is classed as a diabetic neuropathy medicine.
Last reviewed: November 2026. General information only, not medical advice. Contents and strengths can differ by manufacturer and batch, so always check your pack and follow your doctor.
Quick Facts
| Brand | Methoben (Cardeon Formulations) |
| Form | Tablet, strip of 10 |
| Key ingredients | Alpha lipoic acid 100 mg, methylcobalamin (B12) 1000 mcg, benfotiamine 100 mg, folic acid 1.5 mg, pyridoxine (B6) 3 mg, chromium picolinate 200 mcg |
| Used for | Nutritional support and nerve symptoms linked to diabetic neuropathy |
| Prescription | Orders depend on prescription verification where applicable |
| Storage | As per the pack label, in a cool dry place |
Methoben Composition
- Alpha lipoic acid: 100 mg
- Methylcobalamin (vitamin B12): 1000 mcg
- Benfotiamine (a form of vitamin B1): 100 mg
- Folic acid (vitamin B9): 1.5 mg
- Pyridoxine (vitamin B6): 3 mg
- Chromium picolinate: 200 mcg
- Form and pack: tablet, strip of 10. Other Methoben versions such as Methoben CR exist, so check your pack.
What Is Methoben Used For?
- Nutritional support for vitamin deficiency
- Nerve symptoms such as tingling and numbness related to diabetic neuropathy, as advised by a doctor
How It Works
B vitamins support nerve health, benfotiamine is a fat-soluble form of vitamin B1, and alpha lipoic acid is an antioxidant that may protect nerves from damage linked to high blood sugar. Chromium plays a role in how the body handles sugar.
How to Take It
Take it whole with enough water as your doctor or pharmacist advises. The listing gives no fixed dose, so follow your label or prescription.
Possible Side Effects
Possible side effects include:
- Nausea or stomach discomfort
- Headache
- Diarrhoea
- Skin rash
See a doctor if stomach upset or rash does not go away, or if you have signs of an allergy such as swelling or breathing trouble.
Precautions and Who Should Be Careful
- Do not use it if you are allergic to any ingredient.
- Check with your doctor before use in pregnancy, when trying to conceive, or while breastfeeding.
- If you have diabetes, monitor your blood sugar, because alpha lipoic acid and chromium may lower it.
- Tell your doctor about all other medicines and supplements you take.
- Numbness or tingling that continues needs a medical check to find the cause.
Key Points to Remember
- Methoben is a vitamin and antioxidant combination. It is not a painkiller and it does not cure diabetes.
- Blood sugar control, a healthy diet and regular check-ups remain the main way to protect nerves.
- It may lower blood sugar, so people with diabetes should monitor their levels.
When to Contact a Doctor
- Tingling, numbness or burning that is getting worse or spreading
- A foot wound, blister or sore that is slow to heal
- A rash, swelling or breathing trouble after taking it
- Signs of low blood sugar such as shakiness, sweating, confusion or a fast heartbeat
Practical Tips
- Check your feet every day for cuts, blisters or redness and wear well-fitting footwear.
- Keep blood sugar in the range your doctor sets, because high sugar is what damages nerves over time.
- Take it at the same time each day so you do not miss doses.
- Keep a short diary of your symptoms (tingling, numbness, pain) to show your doctor.
Questions to Ask Your Doctor or Pharmacist
- Should my vitamin B12 level be tested before or during treatment?
- Will this change how much diabetes medicine I need?
- How long should I take it before we review my symptoms?
- Is it safe with my other medicines and supplements?
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Helpful Video
Frequently Asked Questions
What is Methoben used for?
Nutritional support and nerve symptoms linked to diabetes, as advised by a doctor.
Is Methoben a tablet or a capsule?
The listing here is a tablet. Methoben CR is sold as a capsule.
Does Methoben lower blood sugar?
It may, so diabetics should monitor their sugar.
Do I need a prescription?
The listing says orders depend on prescription verification where applicable.
How long does Methoben take to work?
Nerve symptoms usually improve slowly, often over weeks to months, and results differ from person to person. Your doctor will review your progress.
Can I take Methoben with metformin?
Many people with diabetes take B-vitamin products alongside metformin, and metformin can lower vitamin B12 levels over time. Ask your doctor to check your B12 and to confirm the combination.
Further reading: NIH Office of Dietary Supplements: Vitamin B12
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